Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

11 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of from Human Umbilical Vein Endothelial Cells

ABSTRACT: We profiled global gene expression in primary human umbilical vein endothelial cells to determine the gene expression changes associated with knocking down PKM2 and p53. We identified a p53 dependent transcriptional response that remodels metabolism in cells lacking p53, thus limiting cell growth. Human Umbilical Vein Endothelial Cells were transfected with siRNA duplexes targeting PKM2 and / or p53, RNA was extracted and subjected to RNA sequencing

ORGANISM(S): Homo sapiens

SUBMITTER: Carsten Kuenne

PROVIDER: E-GEOD-84877 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Effect of from Human Umbilical Vein Endothelial Cells

Project description:We profiled global gene expression in primary human umbilical vein endothelial cells to determine the gene expression changes associated with knocking down PKM2 and p53. We identified a p53 dependent transcriptional response that remodels metabolism in cells lacking p53, thus limiting cell growth.

2016-07-27 | GSE84877 | GEO

MicroRNA expression profile of human umbilical vein endothelial cells treated with Angiogenin (ANG)

Project description:We quantified differential microRNA (miRNA) expression in Human umbilical vein endothelial cells （HUVECs）response to Angiogenin (ANG) treatment.These data were used to determine which miRNAs are altered on ANG in Human umbilical vein endothelial cells.

2016-12-13 | GSE92256 | GEO

Oxidoreductase transcript data from human umbilical vein endothelial cells

Project description:Oxidoreductase enzymes are critical to redox regulation of intracellular proteins within human cells. We used microarrays to identify which oxidreducatse genes are expressed in unstimulated human umbilical vein endothelial cells. Human umbilical vein endothelial cells were grown under optimal conditions and then RNA extracted and hybridized on Affymetrix microarrays.

2010-06-16 | E-GEOD-22166 | biostudies-arrayexpress

Secretome analysis of Human Umbilical Vein Endothelial Cells with PMA treatment using gel-LC-MS/MS

Project description:Secretome analysis of Human Umbilical Vein Endothelial Cells with PMA treatment using gel-LC-MS/MS

2013-09-09 | PRD000733 | Pride

c-MYC target genes in HUVEC

Project description:siRNA mediated knock-down of c-MYC vs. scrambled control in human umbilical vein endothelial cells (HUVEC).

2016-01-11 | E-MTAB-4025 | biostudies-arrayexpress

RNA-seq of CYR61-treated human umbilical vein endothelial cells

Project description:We assess the effect of CYR61 treatment on the transcriptome of human umbilical vein endothelial cells.

2023-10-18 | GSE222101 | GEO

Gene expression profiling of caffeic acid phenethyl ester -treated human umbilical vein endothelial cells

Project description:This SuperSeries is composed of the following subset Series: GSE10413: Gene expression profiling of caffeic acid phenethyl ester-treated human umbilical vein endothelial cells-1 GSE10429: Gene expression profiling of caffeic acid phenethyl ester -treated human umbilical vein endothelial cells-2 Keywords: SuperSeries Refer to individual Series

2010-05-26 | E-GEOD-10465 | biostudies-arrayexpress

Expression data from Human Umbilical Vein Endothelial Cell after influenza virus infection

Project description:This research focus primarily on the interaction between influenza virus and endothelial cell, then we used microarrays to observe global patterns of gene expression in Human Umbilical Vein Endothelial Cells after influenza virus infection and offer further insight into the interaction between endothelial cells and influenza viruses. We used microarrays to detail the global programme of gene expression and identified distinct classes of up-regulated genes during this process. Human Umbilical Vein Endothelial Cells were selected at an early stage for RNA extraction and hybridization on Affymetrix microarrays. Then, we analysed the selected genes at expression level.

2015-04-06 | E-GEOD-59226 | biostudies-arrayexpress

Oxidoreductase transcript data from human umbilical vein endothelial cells

2010-06-05 | GSE22166 | GEO

Effect of overexpression of miR-210-3p on gene expression of human umbilical vein endothelial cells in hypoxic conditions

Project description:To investigate machanism of miR-210-3p regulating angiogenic ability of human umbilical vein endothelial cells (HUVECs) in hypoxic conditions, we transfected miR-210-3p mimic to overexpress miR-210-3p in human umbilical vein endothelial cells. We than performed RNA sequencing of miR-210-3p mimic-transfected and control HUVECs under hypoxic conditions to evaluate the transcriptional changes in the miR-210-3p-overexpressing HUVECs.

2022-09-28 | GSE214170 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data