Transcription profiling of S. cerevisiae response to stress throughout a 15-day wine fermentation

ABSTRACT: We used genome-wide expression analyses to study the response of Saccharomyces cerevisiae to stress throughout a 15-day wine fermentation. Forty percent of the yeast genome significantly changed expression levels to mediate long-term adaptation to an environment in which ethanol is both a stressor and a carbon source. Within this set, we identify a group of 223 genes, designated as the Fermentation Stress Response (FSR), that are dramatically and permanently induced; FSR genes exhibited changes ranging from four-to eighty-fold. The FSR is novel; 62% of the genes involved have not been implicated in global stress responses and 28% of the genes have no functional annotation. Genes involved in respiratory metabolism and gluconeogenesis were expressed during fermentation despite the presence o

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Hennie JJ van Vuuren 

PROVIDER: E-GEOD-8536 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress