Microarray Analysis of chemosensitivity in Hypopharyngeal Squamous Cell Carcinoma

ABSTRACT: OBJECTIVE: To investigate the differentially expressed genes and miRNAs related to the chemosensitivity of hypopharyngeal squamous cell carcinoma （HSCC）by microarrays and miRNA arrays. METHODS: 1. A total number of 21 patients who underwent induction chemotherapy for primary hypopharyngeal squamous cell carcinoma (12 patients are sensitive to chemotherapy ,and others are not) were recruited for microarray and miRNA array gene expression analysis 2. Bioinformatics analysis of differentially expressed genes screened by microarrays : The differential gene cluster analysis was applied in biological processes, cellular components and molecular functions by GO database; The differential gene enrichment analysis was applied in signaling pathways by KEGG database, and the differentially exp

ORGANISM(S): Homo sapiens

SUBMITTER: Jugao Fang 

PROVIDER: E-GEOD-85608 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress