Transcription profiling of mouse 3T3-L1 adipocyte tissue culture treated with tunicamycin

ABSTRACT: Tunycamcin induces UPR/ISR and Inflammation in mouse 3T3-L1 adipocyte tissue culture. The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding to tunicamycin, to be compared with similar experiments with CLA as the treatment. Their gene expression responses between 4 to 12 hr after treatment showed a common set of early gene expression changes indicative of a UPR/Inflammation stress response. Experiment Overall Design: Mouse 3T3-L1 RNA for each time point was isolated from control and treatment samples for analysis on microarrays with two biological reps.

ORGANISM(S): Mus musculus

SUBMITTER: Jean-Jack Riethoven 

PROVIDER: E-GEOD-8682 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress