Transcription profiling of chicken 18 day embryonic chicken heart, brain, and gonad to determine sex specific gene expression

ABSTRACT: The contrasting dose of sex chromosomes in males and females potentially introduces a large-scale imbalance in levels of gene expression between sexes. In many organisms dosage compensation has thus evolved to equalize sex-linked gene expression in males and females1,2, in mammals achieved by X chromosome inactivation and in flies and worms by up- or down-regulation of X-linked expression, respectively. Another form of dosage compensation ensures that expression levels on the X chromosome and on autosomes are balanced3,4. While otherwise widespread in systems with heteromorphic sex chromosomes, the case of dosage compensation in birds (males ZZ, females ZW) remains an unsolved enigma5,6. Here we use a microarray approach to show that male day 18 chicken embryos generally express higher lev

ORGANISM(S): Gallus gallus

SUBMITTER: judith mank 

PROVIDER: E-GEOD-8693 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress