Chromosomal clustering of genes in absent, small, or homeotic discs 2 (ash2) mutant larvae
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Adrià Punset
PROVIDER: E-GEOD-8750 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila.
Blanco Enrique E Pignatelli Miguel M Beltran Sergi S Punset Adrià A Pérez-Lluch Silvia S Serras Florenci F Guigó Roderic R Corominas Montserrat M
Genome biology 20080910 9
<h4>Background</h4>The trithorax group (trxG) and Polycomb group (PcG) proteins are responsible for the maintenance of stable transcriptional patterns of many developmental regulators. They bind to specific regions of DNA and direct the post-translational modifications of histones, playing a role in the dynamics of chromatin structure.<h4>Results</h4>We have performed genome-wide expression studies of trx and ash2 mutants in Drosophila melanogaster. Using computational analysis of our microarray ...[more]
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