Transcription profiling of Anopheles gambiae response to bloodmeal

ABSTRACT: With their genome sequenced, Anopheles gambiae mosquitoes now serve as a powerful tool for basic research in comparative, evolutionary and developmental biology. The knowledge generated by these studies is expected to reveal molecular targets for novel vector control and pathogen transmission blocking strategies. Comparisons of gene-expression profiles between adult male and nonblood-fed female Anopheles gambiae mosquitoes revealed that roughly 22% of the genes showed sex-dependent regulation. Blood-fed females switch the majority of their metabolism to blood digestion and egg formation within 3 h after the meal is ingested, in detriment to other activities such as flight and response to environment stimuli. Changes in gene expression are most evident during the first, second and third day

ORGANISM(S): Anopheles gambiae

SUBMITTER: Osvaldo Marinotti 

PROVIDER: E-GEOD-8822 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress