LmrR Lactococcus lactis MG1363
Ontology highlight
ABSTRACT:
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363
SUBMITTER: Anne Jong
PROVIDER: E-GEOD-9168 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
LmrR is a transcriptional repressor of expression of the multidrug ABC transporter LmrCD in Lactococcus lactis.
Agustiandari Herfita H Lubelski Jacek J van den Berg van Saparoea H Bart HB Kuipers Oscar P OP Driessen Arnold J M AJ
Journal of bacteriology 20071109 2
LmrCD is an ABC-type multidrug transporter in Lactococcus lactis. LmrR encodes a putative transcriptional regulator. In a DeltalmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD and interacts with drugs that cause lmrCD up-regulation. This suggests that LmrR is a drug-dependent transcriptional regulator of lmrCD expression. ...[more]
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