Transcription profiling of rat REF52 cells reveals an E2F1-dependent gene expression program that determines the balance between proliferation and cell death

ABSTRACT: E2F1 has been shown to induce both proliferation and apoptosis. We now show that PI3K/Akt signaling regulates the balance of these events by specifically blocking expression of genes in the E2F1 apoptotic program but not the proliferative program. Experiment Overall Design: 11 samples total, two replicates each (except Sample 1 which is represented once)

ORGANISM(S): Rattus norvegicus

SUBMITTER: Timothy Hallstrom 

PROVIDER: E-GEOD-9496 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress