Comparative Genomic Analysis of Clinical Strains of Campylobacter jejuni from South Africa

ABSTRACT: Background. The bacterial foodborne pathogen Campylobacter jejuni is a common cause of acute gastroenteritis and is also associated with the postinfectious neuropathies, Guillain-Barré and Miller Fisher syndromes. This study described the use of multilocus sequence typing and DNA microarrays to examine the genetic content of a collection of South African C. jejuni strains, recovered from patients with enteritis, Guillain-Barré or Miller Fisher syndromes. Methodology/Principal Findings. The comparative genomic analysis by using multilocus sequence typing and DNA microarrays demonstrated that the South African strains with Penner heat-stable (HS) serotype HS:41 were clearly distinct from the other South African strains. Further analysis of the DNA microarray data demonstrated that the

ORGANISM(S): Campylobacter jejuni

SUBMITTER: Craig Parker 

PROVIDER: E-GEOD-9862 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress