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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human BM-MSC expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability

ABSTRACT: hBM-MSC were expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability;ÃÂµA analysis were performed p2/p5 (n=10)and p5/p10 (n=5) to examine if the genetic background of hBM-MSC is changeing during their high-grade expansion;

ORGANISM(S): Homo sapiens

SUBMITTER: paar Christine Paar

PROVIDER: E-MARS-6 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation.

Kulterer Birgit B Friedl Gerald G Jandrositz Anita A Sanchez-Cabo Fatima F Prokesch Andreas A Paar Christine C Scheideler Marcel M Windhager Reinhard R Preisegger Karl-Heinz KH Trajanoski Zlatko Z

BMC genomics 20070312

<h4>Background</h4>Human mesenchymal stem cells (MSC) with the capacity to differentiate into osteoblasts provide potential for the development of novel treatment strategies, such as improved healing of large bone defects. However, their low frequency in bone marrow necessitate ex vivo expansion for further clinical application. In this study we asked if MSC are developing in an aberrant or unwanted way during ex vivo long-term cultivation and if artificial cultivation conditions exert any influ ...[more]

PMID: 17352823

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2007-06-09 | E-MARS-4 | biostudies-arrayexpress

Transcription profiling of human BM-MSC expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability

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Transcription profiling of wild type and A-C/EBP transgenic mouse embryonic fibroblasts during adipogenesis to identify C/ebp alpha target genes

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2010-04-27 | E-MARS-14 | biostudies-arrayexpress

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2010-03-26 | E-MARS-17 | biostudies-arrayexpress

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