Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of brain tissue from trout with different dominace status


ABSTRACT: Dominance hierarchies of rainbow trout Trout form linear dominance hierarchies where there is a dominant, subdominant and subordinate. The dominant is the most aggressive, followed by the subdominant and the subordinate is the least dominant. Fish were scored on their aggressive performance to calculate position within the hierarchy, and once formed the hierarchies are very stable. Hypothesis: Gene expression is different in the brains of individuals with different dominance status. Six hierarchies containing a dominant, subdominant and subordinate were assessed behaviourally then killed and the brain removed. These were run in a reference based design. Hypothesis: On removal of the dominant the subdominant fish will become dominant and its transcript profile will become similar to the established dominant. The second experiment involved removing the dominant from an established hierarchy and then examining gene expression at 2hr, 48hr and 1 week in the new dominant.

ORGANISM(S): Oncorhynchus mykiss

SUBMITTER: Michael Wilson 

PROVIDER: E-MAXD-33 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Molecular correlates of social dominance: a novel role for ependymin in aggression.

Sneddon Lynne U LU   Schmidt Rupert R   Fang Yongxiang Y   Cossins Andrew R AR  

PloS one 20110405 4


Theoretical and empirical studies have sought to explain the formation and maintenance of social relationships within groups. The resulting dominance hierarchies have significant fitness and survival consequences dependent upon social status. We hypothesised that each position or rank within a group has a distinctive brain gene expression profile that correlates with behavioural phenotype. Furthermore, transitions in rank position should determine which genes shift in expression concurrent with  ...[more]

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