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MicroRNA profiling of human prostate cancer cell lines, xenografts and tumor samples


ABSTRACT: miRNA expression profiling in 6 prostate cancer cell lines, 9 prostate cancer xenografts, and 13 clinical prostate tumor samples

INSTRUMENT(S): Typhoon TRIO

ORGANISM(S): Homo sapiens

DISEASE(S): prostate cancer

SUBMITTER: Kati Porkka 

PROVIDER: E-MEXP-1058 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

MicroRNA expression profiling in prostate cancer.

Porkka Kati P KP   Pfeiffer Minja J MJ   Waltering Kati K KK   Vessella Robert L RL   Tammela Teuvo L J TL   Visakorpi Tapio T  

Cancer research 20070701 13


MicroRNAs (miRNA) are small, endogenously expressed noncoding RNAs that negatively regulate expression of protein-coding genes at the translational level. Accumulating evidence, such as aberrant expression of miRNAs, suggests that they are involved in the development of cancer. They have been identified in various tumor types, showing that different sets of miRNAs are usually deregulated in different cancers. To identify the miRNA signature specific for prostate cancer, miRNA expression profilin  ...[more]

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