Transcription profiling of mouse spermatagonia stimulated with kit ligand, bone morphogenetic protein 4 (BMP4) or all-trans retinoic acid
Ontology highlight
ABSTRACT:
INSTRUMENT(S): other
ORGANISM(S): Mus musculus
SUBMITTER: Pellegrino Rossi
PROVIDER: E-MEXP-1126 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Transcriptome analysis of differentiating spermatogonia stimulated with kit ligand.
Rossi Pellegrino P Lolicato Francesca F Grimaldi Paola P Dolci Susanna S Di Sauro Annarita A Filipponi Doria D Geremia Raffaele R
Gene expression patterns : GEP 20071025 2
Kit ligand (KL) is a survival factor and a mitogenic stimulus for differentiating spermatogonia. However, it is not known whether KL also plays a role in the differentiative events that lead to meiotic entry of these cells. We performed a wide genome analysis of difference in gene expression induced by treatment with KL of spermatogonia from 7-day-old mice, using gene chips spanning the whole mouse genome. The analysis revealed that the pattern of RNA expression induced by KL is compatible with ...[more]
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