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Transcription profiling time series of human epithelial cells during development

ABSTRACT: The experiment was designed to generate a time series for epithelial model during development. Each time point had 3 replicates. The data set contained 5 time points over 10 days. They are day0, day3, day5,day7,day10.

ORGANISM(S): Homo sapiens

SUBMITTER: Lizhong Hao

PROVIDER: E-MEXP-1130 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes.

Taylor Jennifer M JM Street Teresa L TL Hao Lizhong L Copley Richard R Taylor Martin S MS Hayden Patrick J PJ Stolper Gina G Mott Richard R Hein Jotun J Moffatt Miriam F MF Cookson William O C M WO

PloS one 20091030 10

The mammalian epidermis is a continually renewing structure that provides the interface between the organism and an innately hostile environment. The keratinocyte is its principal cell. Keratinocyte proteins form a physical epithelial barrier, protect against microbial damage, and prepare immune responses to danger. Epithelial immunity is disordered in many common diseases and disordered epithelial differentiation underlies many cancers. In order to identify the genes that mediate epithelial dev ...[more]

PMID: 19888454

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recombinant human epidermal model LC-MS/MS

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