Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of human colon Caco2 cells treated with extracts from broccoli that had been cooked for different lengths of time


ABSTRACT: Caco2 cells were treated 24 hours with broccoli extracts that had been cooked for different lengths of time.

ORGANISM(S): Homo sapiens

SUBMITTER: Caroline Furniss 

PROVIDER: E-MEXP-1372 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Polyamine metabolism and transforming growth factor-beta signaling are affected in Caco-2 cells by differentially cooked broccoli extracts.

Furniss Caroline S M CS   Bennett Richard N RN   Bacon James R JR   LeGall Gwen G   Mithen Richard F RF  

The Journal of nutrition 20081001 10


The health benefits of consuming cruciferous vegetables are widely considered to be due to the biological activity of glucosinolate degradation products. However, it is conceivable that other phytochemicals within crucifers may also have biological activity that may contribute to health benefits. In this study, we analyzed global gene expression in Caco-2 cells exposed to extracts derived from broccoli that had been heat treated to different extents to result in contrasting profiles of glucosino  ...[more]

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