Transcription profiling by array of human HL60 cells treated with eicosapantaenoic acid (EPA) to investigate the effect on the signalling pathways involved in growth arrest/apoptosis

ABSTRACT: We investigated the effect of EPA on the signalling pathways involved in growth arrest/apoptosis in HL60 cells. EPA inhibited cell proliferation in HL60 cells in a dose dependent manner. Gene expression profiling of HL60 cells treated with EPA was performed by Affymetrix GeneChip. System and key markers of relevant pathways were verified at protein level by western blotting.

ORGANISM(S): Homo sapiens

SUBMITTER: Caroline Jakobsen 

PROVIDER: E-MEXP-1389 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress