Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomic hybridization of three Streptococcus pneumoniae strains

ABSTRACT: We performed a comparative study of the two control sample options with a Streptococcus pneumoniae microarray designed with three fully sequenced strains. We hybridized two of these strains (R6 and G54) as test samples using the third strain alone (TIGR4) or a mix of the three strains as the control sample.

INSTRUMENT(S): G2565BA DNA microarray scanner [Agilent]

ORGANISM(S): Streptococcus pneumoniae

SUBMITTER: Francisco Pinto 

PROVIDER: E-MEXP-1390 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Optimal control and analysis of two-color genomotyping experiments using bacterial multistrain arrays.

Pinto Francisco R FR   Aguiar Sandra I SI   Melo-Cristino J J   Ramirez Mário M  

BMC genomics 20080519

<h4>Background</h4>Microarray comparative genomic hybridization (aCGH) evaluates the distribution of genes of sequenced bacterial strains among unsequenced strains of the same or related species. As genomic sequences from multiple strains of the same species become available, multistrain microarrays are designed, containing spots for every unique gene in all sequenced strains. To perform two-color aCGH experiments with multistrain microarrays, the choice of control sample can be the genomic DNA  ...[more]

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