Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of human colon cancer cell line SW480 expressing ERb and then treated with estrogen or untreated

ABSTRACT: Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERb-mediated gene regulation in the SW480 colon cancer cell line. The colon cancer cell line SW480 does not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ERb expression cassette. Introduction of ERb makes it possible to study the role and function of ERb in colon cancer as well as the impact ERb has on its own (in the absence of ERa).

ORGANISM(S): Homo sapiens

SUBMITTER: Karin Edvardsson

PROVIDER: E-MEXP-1473 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling of human colon cancer cell line - ligand independent control

Project description:Control experiment to confirm ligand independent effect on gene regulation by ERb in HT29 cells. The colon cancer cell lines do not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ERb expression cassette. Introduction of ERb makes it possible to study the role and function of ERb in colon cancer as well as the impact ERb has on its own (in the absence of ERa).

2011-05-29 | E-MEXP-3176 | biostudies-arrayexpress

Transcription profiling of human colon cancer cell lines

Project description:Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERb-mediated gene regulation in the two colon cancer cell lines HCT116 and HT29. The colon cancer cell lines do not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ERb expression cassette. Introduction of ERb makes it possible to study the role and function of ERb in colon cancer as well as the impact ERb has on its own (in the absence of ERa).

2011-04-15 | E-MEXP-3169 | biostudies-arrayexpress

Transcription profiling of breast cancer cells with TET-OFF regulated ERb expression treated with estradiol or ICI, an estrogen receptor antagonist

Project description:Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERa and ERb-mediated gene regulation in T47D breast cancer cell line with TET-OFF regulated ERb expression.

2007-12-17 | E-MEXP-969 | biostudies-arrayexpress

Transcription profiling of mouse epithelial cell line HC11which have stem cell characteristics during stem cell differentiation

Project description:In this study we have used a murine mammary epithelial cell line (HC11) with stem cell characteristics and made a thorough investigation of global gene-expression changes during mammary stem cell differentiation.

2009-09-18 | E-MEXP-1809 | biostudies-arrayexpress

Transcription profiling of N. gonorrhoeae nmb1650 knockout mutant and parental strains grown in capnoaerobic conditions

Project description:Comparison of N. gonorrhoeae nmb1650 knockout mutant and wild-type parent strains grown in capnoaerobic conditions (normal atmosphere +5% CO2)

2011-05-01 | E-MEXP-1664 | biostudies-arrayexpress

Transcription profiling of N. meningitidis nmb1650 knockout mutant and parental strains grown in capnoaerobic conditions

Project description:Comparison of N. meningitidis nmb1650 knockout mutant and parental strains grown in capnoaerobic conditions (normal atmosphere +5% CO2)

2010-05-01 | E-MEXP-1666 | biostudies-arrayexpress

Transcription profiling of N. meningitidis nmb1650 knockout mutant and parental strains grown in anaerobic conditions

Project description:Comparison of N. meningitidis nmb1650 knockout mutant and parental strains grown in anaerobic conditions

2011-05-01 | E-MEXP-1667 | biostudies-arrayexpress

Transcription profiling of N. gonorrhoeae nmb1650 knockout mutant and parental strains grown in anaerobic conditions

Project description:Comparison of N. gonorrhoeae nmb1650 knockout mutant and parental wild-type strains grown in anaerobic conditions

2011-05-01 | E-MEXP-1665 | biostudies-arrayexpress

Transcription profiling of Drosophila Kc167 cells following 5-48 hr treatment with 20-hydroxyecdysone

Project description:The changes in transcript titers are described for Drosophila Kc167 cells following 5-48 hr treatment with 20-hydroxyecdysone.

2009-05-01 | E-MEXP-1603 | biostudies-arrayexpress

AtMYB60

Project description:Stomatal guard-cells modulate gas exchange between the plant and the atmosphere. Regulation of transcription is emerging as an important mechanism in controlling guard cells activity. The Arabidopsis transcription factor AtMYB60, is specifically expressed in guard cells and controls stomatal movements. Opening of stomatal pores is constitutively reduced in the atmyb60-1 null allele, and water loss during drought is diminished in the mutant compared to wild type. To address the effect of the AtMYB60 disruption on global gene expression, total mRNAs, derived from atmyb60-1 and WT rosette leaves, grown in standard conditions, were hybridized to a cDNA microarray.

2005-01-10 | E-MEXP-225 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data