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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Candida albicans clinical isolates

ABSTRACT: Comparison of 20 clinical isolates of Candida albicans grown under identical growth conditions (biofilm growth conditions in RPMI 1640/10% serum)

ORGANISM(S): Candida albicans

SUBMITTER: AFG AFG

PROVIDER: E-MEXP-1933 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Property differences among the four major Candida albicans strain clades.

MacCallum Donna M DM Castillo Luis L Nather Kerstin K Munro Carol A CA Brown Alistair J P AJ Gow Neil A R NA Odds Frank C FC

Eukaryotic cell 20090116 3

A selection of 43 Candida albicans isolates, chosen to represent the four major strain clades of the species and also intraclade diversity, was screened for their virulence in the murine intravenous challenge model of C. albicans infection, for a range of properties measurable in vitro that might relate to virulence, and for the numbers of midrepeat sequences in genes of the ALS and HYR families. Heterozygosity at the mating type locus and low whole-cell acid phosphatase activity and growth rate ...[more]

PMID: 19151328

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