Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

MicroRNA profiling of human precursor B-cell acute lymphoblastic leukemia cell line NALM-6 after trichostatin A treatment

ABSTRACT: Expression profile of miRNAs in NALM-6 cells were analyzed after TSA treatment for 6h, compared with non-treated cells.

ORGANISM(S): Homo sapiens

SUBMITTER: Xian-Ming Chen 

PROVIDER: E-MEXP-2047 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation.

Li Xiaoqing X   Liu Jun J   Zhou Rui R   Huang Shi S   Huang Shiang S   Chen Xian-Ming XM  

British journal of haematology 20091005 1

Aberrant epigenetic regulation has recently been implicated in the downregulation of tumour suppressor microRNAs (miRNAs). Histone modification and DNA methylation can have different roles in gene silencing in cancer. To investigate whether histone modifications would contribute to the dysregulation of miRNAs in acute lymphoblastic leukaemia (ALL), the effect of a histone deacetylase inhibitor, trichostatin A (TSA), on miRNA expression profile was analysed by microarray assay in a precursor B-ce  ...[more]

Similar Datasets

Transcriptomics MicroRNA profiling of human cholangiocyte H69 cells after exposure to tumor necrosis factor-alpha
2011-01-01 | E-MEXP-2049 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human cholangiocyte H69 cells after culturing with lipopolysaccharide
2010-02-11 | E-MEXP-2052 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human cholangiocyte H69 cells after infection with Cryptosporidium parvum
2010-02-11 | E-MEXP-2050 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human cholangiocytes in response to interferon-gamma
2009-02-10 | E-MEXP-1906 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human healthy, psoriasis and atopic eczema skin samples
2007-08-16 | E-MEXP-1123 | biostudies-arrayexpress
Transcriptomics miRNA profile of five hematopoietic cell lines
2014-09-01 | E-MEXP-3944 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human neuroblastoma cells shows MYCN-regulated MicroRNAs repress estrogen receptor-alpha expression
2009-04-01 | E-MEXP-2006 | biostudies-arrayexpress
Transcriptomics Expression of microRNAs and their target mRNAs in hESC-derived cardiomyocyte clusters and in heart tissue_microRNA_data
2011-03-30 | E-MEXP-2655 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human peripheral blood leukocytes before and after stimulation with E. coli lipopolysaccharide
2008-12-01 | E-MEXP-1860 | biostudies-arrayexpress
Transcriptomics OncomiR-21 triggers growth arrest of endothelial cells via a complex network involving p21 CDK2 CDC25A and NFIB
2013-01-17 | E-MEXP-3596 | biostudies-arrayexpress