Transcription profiling of rat heart after ischaemia reperfusion injury and then treatment with saline, urocortin I, urocortin II or tempol

ABSTRACT: The transcriptional effects of urocortin I, urocortin II and tempol were compared to saline treatment in a rat model of in vivo coronary artery occlusion model of ischaemia/reperfusion injury of 25 min ischaemia and 2 hr reperfusion.
The treatment groups were as follows (i) sham operation or LAD occlusion with infusion of (ii) saline, (iii) 15 ?g/kg Ucn I, (iv) 15 ?g/kg Ucn II and (v) 100 mg/kg tempo infused just prior to reperfusionl.
Following 2 hr reperfusion the left ventricle was removed, snap frozen, followed by RNA extraction.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Sean Barry 

PROVIDER: E-MEXP-2098 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress