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Transcription profiling of Bacillus anthracis Sterne during iron starvation

ABSTRACT: Effects of iron starvation on the transcriptional profile of Bacillus anthracis

ORGANISM(S): Bacillus anthracis

SUBMITTER: Paul Carlson

PROVIDER: E-MEXP-2272 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptional profiling of Bacillus anthracis Sterne (34F2) during iron starvation.

Carlson Paul E PE Carr Katherine A KA Janes Brian K BK Anderson Erica C EC Hanna Philip C PC

PloS one 20090921 9

Lack of available iron is one of many environmental challenges that a bacterium encounters during infection and adaptation to iron starvation is important for the pathogen to efficiently replicate within the host. Here we define the transcriptional response of B. anthracis Sterne (34F(2)) to iron depleted conditions. Genome-wide transcript analysis showed that B. anthracis undergoes considerable changes in gene expression during growth in iron-depleted media, including the regulation of known an ...[more]

PMID: 19768119

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