Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

160 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of human thyroid follicular adenomas and thyroid papillary carcinomas to discriminate benign and malignant tumors

ABSTRACT: Identification of a stable gene expression signature with high classifying potential to discriminate benign (Follicular adenomas) and malignant (papillary carcinomas) thyroid tumors

ORGANISM(S): Homo sapiens

DISEASE(S): normal

SUBMITTER: nicolas ugolin

PROVIDER: E-MEXP-2335 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

HK_CIA_experiment

Project description:In previous studies, we identified the fungal macrocyclic lactone (S)-curvularin (SC) as an anti-inflammatory agent using a screening system detecting inhibitors of the Janus kinase/signal transducer and activator of transcription pathway. The objective of the present study was to investigate whether SC is able to decrease proinflammatory gene expression in an in vivo model of a chronic inflammatory disease. Therefore, the effects of SC and dexamethasone were compared in the model of collagen-induced arthritis (CIA) in mice. In addition to measuring the arthritis index (paw swelling) of the animals, we also performed whole genome microarray analyses to identify SC target genes and new therapeutic targets of SC.

2012-09-21 | E-MEXP-3180 | biostudies-arrayexpress

GM - E. coli - SetB LZ fishns Hyp Rel

Project description:Comparison of transcript profiles of E. coli LZ41 and LZ54 fishns mutant strains containing drug-resistant alleles of different topoisomerase genes to distinguish gene transcripts associated either with relaxation or hypernegative supercoiling in absence of transcriptional regulator FIS and H-NS.

2011-01-07 | E-MEXP-3049 | biostudies-arrayexpress

GM - E. coli - LZ fishns Act Rep

Project description:Comparison of transcript profiles of E. coli LZ41fishns and LZ54fishns strains containing drug-resistant alleles of different topoisomerase genes to distinguish gene transcripts associated either with relaxation or hypernegative supercoiling.

2011-01-07 | E-MEXP-3050 | biostudies-arrayexpress

Transcription profiling of T. brucei trypanosomes during differentiation reveals the existence of multiple post-transcriptional regulons.

Project description:We analysed differentiation of the EATRO1125 strain of Trypanosoma brucei brucei, which was first isolated in 1966 from a bushbuck (Tragelaphus scriptus) in Uganda (origin stated (Bouteillea, 1995) without an original reference. To analyse gene expression, we isolated at least 3 x 10e8 trypanosomes at different differentiation states, using two independent biological replicates. Bloodstream forms were harvested at a density of 2 x 10e5/ml (low density, logarithmic growth), and 2 x 10e6/ml (high density, logarithmic growth). Cells were also taken immediately upon attaining the density of 2 x 106/ml, treated with 3 mM cis-aconitate and moved to a room at 27M-0C. Samples were taken 30 min, 60 min, 12h and 24h after this. At 24 h the cells were centrifuged, resuspended (at 27M-0C) in MEM-Pros medium, which contains proline as the major energy source. Samples were taken again at 48h and 72h. A culture that had been maintained for several weeks after transformation was used as a source of established procyclic trypanosomes.

2010-01-01 | E-MEXP-2027 | biostudies-arrayexpress

miRNA dysregulation in AMI serum

Project description:To detect the dysregulated miRNAs in the serum of acute myocardial infarction patients.

2012-04-30 | E-MEXP-3578 | biostudies-arrayexpress

Bud dormancy in different peach cultivars

Project description:Correlation analysis of the expression of bud dormancy-related genes in 10 peach cultivars, with different chilling requirements for dormancy release.

2012-01-15 | E-MEXP-3201 | biostudies-arrayexpress

CENAT-H.sapiens-Allergy-ded1

Project description:Comparison of gene expression profiles between pediatric patients with and without symptoms of cross-allergy (birch-apple syndrome).

2013-10-11 | E-MEXP-3633 | biostudies-arrayexpress

CENAT-H.sapiens-Asthma-ded1

Project description:transcription profiling of selected genes in pediatric patients suffering from asthma

2013-10-11 | E-MEXP-3646 | biostudies-arrayexpress

Pathochip of Streptococcus spp surface proteins

Project description:In order to appreciate the presence of surface protein gene homologues in commensal species S. mitis and S. oralis, comparative genomic hybridization studies using DNA microarrays were performed with 8 S. mitis and 11 S. oralis from different geographic locations. The oligonucleotide microarray was designed based on the genomes of S. pneumoniae R6 and TIGR4 as well as S. mitis B6 to include genes of 63 cell surface proteins. The denatured genomic DNA of the S. mitis and S. oralis strains was labeled with Cy3-dCTP and control S. mitis B6 DNA was labeled with Cy5-dCTP. Hybridization was performed following the manufacturers recommendations using an hybridization temperature of 40C for 16 h. For data processing, microarrays were scanned on the laser scanner Pro Scan Array GX (PerkinElmer) with the low resolution of 50 M-5m using ScanArrayExpress Software version 4.0. Photomultiplier tube was adjusted to balance the two fluorescence channels and biochips were scanned with a resolution of 10 M-5m. After elimination of background values fluorescence intensity was determined. Signals that showed an intensity ratio of 0.3 and above were considered to be positive.

2011-09-15 | E-MEXP-3360 | biostudies-arrayexpress

Transcript profiling of the wild type Arabidopsis grown under different photoperiods

Project description:Arabidopsis rosette leaves were harvested from plants grown under different photoperiods under 100 M-5mol photons m-2 s-1 at 20 M-0C. In the first experiment plants grown under short day conditions 8L/16D (8 h light / 16 h dark) for 4 weeks were compared with plants grown under long day (16L/8D) for 3 weeks. In the second experiment plants grown under 12L/12D for 2 weeks were compared with plants grown first 2 weeks under 12L/12D and then two days under short day (8L/16D) conditions.

2012-07-27 | E-MEXP-3331 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data