Comparative genomic hybridization of normal karyotype lung tumors from heavy smokers using Affymetrix SNP arrays

ABSTRACT: Whole genome analysis on normal karyotype lung tumors from heavy smokers.
Our study regarded a population of 5203 heavy smokers volunteers, enrolled in a screening program set up at the European Institute of Oncology. Each volunteer yearly undergoes low dose CT-scan. At the end of the second year, among 89 screening-identified patients with lung cancers, 57 cases with clinical localized lung malignancy were evaluated for the present analysis. These, together with 21 other asymptomatic patients (pilot population), carrying non-screening detected lung cancers, but with same characteristics of the screened population (asymptomatic, smokers, older than 50, with an occasionally detected localized cancer), constituted our study population (78 cases). At the time of surgical resecti

ORGANISM(S): Homo sapiens

DISEASE(S): normal tissue

SUBMITTER: Elena Belloni 

PROVIDER: E-MEXP-2450 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress