Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

14 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling of human immortalized pancreatic islet endothelial cells incubated with EPC-derived microvesicles

ABSTRACT: Endothelial cells derived from freshly purified human islets were incubated with microvesicles collected by ultracentrifugation of supernatants of endothelial progenitor cells (EPCs) isolated from peripheral blood of healthy volunteers.

ORGANISM(S): Homo sapiens

SUBMITTER: Vincenzo Cantaluppi

PROVIDER: E-MEXP-2511 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling of human proximal tubular epithelial cells inclubated with 5% plasma from septic patients or healthy volunteers

Project description:proximal tubular epithelial cell apoptosis were incubated with 5% plasma of septic patients or healthy volunteers diluited in RPMI 1640

2008-03-15 | E-MEXP-1510 | biostudies-arrayexpress

Transcription profiling by array of human islet endothelial cells (hIECs) stimulated with or without 50 ug/ml of islet-derived extracellular vesicles for 12 and 24 hours.

Project description:Human islet endothelial cells (hIECs) were stimulated or not with 50 ug/ml of islet-derived EVs for 12 and 24 hours.

2012-08-08 | E-MEXP-3693 | biostudies-arrayexpress

Tubular epithelial cells cisplatin and EPC EVs apoptosis

Project description:Renal tubular epithelial cells were treated with cisplatin in presence or absence of EPC-derived EVs

2013-09-30 | E-MEXP-3981 | biostudies-arrayexpress

microRNA expression profile in isolated human pancreatic islets and in human pancreatic islet-derived extracellular vesicles -EVs-

Project description:Human pancreatic islets were isolated from pancreas of deceased donors by Ricordi's procedure and cultured in CMRL 1066 medium additioned with human albumin. EVs were isolated from conditioned medium derived from islet culture after isolation. Once isolated, RNA of islets and islet-derived EVs was extracted and analyzed for microRNA expression within 48 hours after isolation.

2012-07-30 | E-MEXP-3691 | biostudies-arrayexpress

transcriptional profile of islet EVs for diabetes genes

Project description:Identification of transcriptional profile of several genes involved in diabetes in islet-derived extracellular vesicles (Evs). Recently, EVs are identified as a new mechanism in cell-to-cell communication by transfer of protein and genic information (mRNA, microRNA). Their role is under investigation in immunology, stem cell and cancer, but not in islets and diabetes. The aim of this experiment is to identify mRNA transcripts (in particular, mRNA transcripts involved in diabetes pathophysiology) present in islet Evs.

2012-08-02 | E-MEXP-3695 | biostudies-arrayexpress

Hypoxic tubular endothelium and EPC MVs

Project description:Tubular endothelial cells were cultured in hypoxic conditions (1% O2) and treated or not with microvesicles derived from endothelial progenitor cells.<br>mRNA profiling of hypoxic cells, treated or not with MVs, was analyzed after nromalization with mRNA profiling of normoxic cells.<br><br>This experiment was updated on 27th Jan 2011 to correct descriptions.

2011-01-29 | E-MEXP-2972 | biostudies-arrayexpress

MicroRNA profiling by arryay of human endothelial progenitor cells cultured in normoxic or hypoxic conditions

Project description:microRNA expression profile in endothelial progenitor cells cultured in normoxic and hypoxic condition

2010-08-16 | E-MEXP-2855 | biostudies-arrayexpress

Huvec angiogenesis in hypoxic condition treated with caffeic acid

Project description:HUVECs were cultured in hypoxic conditions for 24 hours and treated or not with 1uM caffeic acid. Then cells were evaluated for expression of different genes involved in angiogenesis

2013-06-03 | E-MEXP-3908 | biostudies-arrayexpress

Apoptosis in normoxic and hypoxic tubular epithelial cells treated with EPC MVs

Project description:TECs cultured in normoxic conditions, TECs cultured in hypoxic conditions and TECs cultured in hypoxic treated with EPc derived microvesicles

2011-02-04 | E-MEXP-3086 | biostudies-arrayexpress

Transcription profiling time series of D.melanogaster testis

Project description:Gene transcription in Drosophila melanogaster testis was compared at different stages of development.

2010-01-01 | E-MEXP-1980 | biostudies-arrayexpress