Transcription profiling by array of Mycobacterium avium subsp. paratuberculosis cattle and sheep strains grown under in vitro iron limiting or iron sufficient conditions

ABSTRACT: Transcriptional responses of two strain types of Mycobacterium avium subsp. paratuberculosis (MAP, cattle and sheep Strain) under in vitro iron limiting or iron sufficient growth conditions. Background: In MAP, the transcriptional role and essentiality of MAP2827 (IdeR) as an iron dependent regulator has been well established (Janagama et al. 2009). Therefore, in the absence of an ideR deletion mutant of MAP, to understand the genome-wide iron dependent transcriptional variations between the cattle and sheep MAP IdeR we used a heterologous expression of MAP IdeR in Mycobacterium smegmatis ideR deletion mutant.

ORGANISM(S): Mycobacterium avium subsp. paratuberculosis

SUBMITTER: Harish Janagama 

PROVIDER: E-MEXP-2865 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress