Transcription profiling by array of Aedes aegypti infected with Wolbachia strains wMelPop and wMel

ABSTRACT: Wolbachia is a vertically transmitted intracellular bacteria that infect most than 60% of insect species. The strains wMelPop and wMel were introduced in the dengue virus vector Aedes aegypti, naturally not infected by Wolbachia. Recently, it was shown that those two strains inhibit dengue virus replication into their new host, A. aegypti (Moreira et al. 2009 and Walker et al. in preparation). The aim of this project is to look at the transcriptional response of Aedes aegypti to infection with wMel and wMelPop and try to find some genes or pathway potentially involved in the viral interference.Four laboratory lines of A. aegypti were used throughout this study. The PGYP1 and Mel2 lines were generated by transinfection with wMelPop and wMel strains respectively. PGYP1.tet and Mel2tet lines

ORGANISM(S): Aedes aegypti

DISEASE(S): not infected

SUBMITTER: Edwige Rances 

PROVIDER: E-MEXP-2931 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress