Transcription profiling of human T-ALL patients at diagnosis and relapse

ABSTRACT: A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 104 samples; Affymetrix U133A micro-arrays.

Ninety two patients with T-ALL were diagnosed and treated at Saint-Louis hospital, Paris. Seven patients were studied at diagnosis and relapse (total 99 T-ALL samples). There were 56 children (median age 9 years old; range 1 to 16), and 36 adults (median age 27; range 17 to 66). Informed consent was obtained from the patients and/or relatives. T-ALL diagnosis was based on morphological and immunophenotypical criteria using flow cytometry and an extended monoclonal antibody panel.

Using a combination of molecular cytogenetic and large-scale expression analysis in human T-ALL, we identified and characteri

ORGANISM(S): Homo sapiens

DISEASE(S): precursor T lymphoblastic leukemia

SUBMITTER: Herve Dombret 

PROVIDER: E-MEXP-313 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress