Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

KT2440 wt vs. Mut agmR chloramphenicol

ABSTRACT: Transcriptional profile comparison of P. putida KT2440 and its isogenic mutant in agmR gene, both grown in minimal medium with added chloramphenicol (25 mg/mL)

ORGANISM(S): Pseudomonas putida

SUBMITTER: Matilde Fernandez

PROVIDER: E-MEXP-3206 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Mechanisms of resistance to chloramphenicol in Pseudomonas putida KT2440.

Fernández Matilde M Conde Susana S de la Torre Jesús J Molina-Santiago Carlos C Ramos Juan-Luis JL Duque Estrella E

Antimicrobial agents and chemotherapy 20111205 2

Pseudomonas putida KT2440 is a chloramphenicol-resistant bacterium that is able to grow in the presence of this antibiotic at a concentration of up to 25 μg/ml. Transcriptomic analyses revealed that the expression profile of 102 genes changed in response to this concentration of chloramphenicol in the culture medium. The genes that showed altered expression include those involved in general metabolism, cellular stress response, gene regulation, efflux pump transporters, and protein biosynthesis. ...[more]

PMID: 22143519

Dataset Information

KT2440 wt vs. Mut agmR chloramphenicol

Publications

Mechanisms of resistance to chloramphenicol in Pseudomonas putida KT2440.

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