Dataset Information
RogB mutant in NEM316 S. agalactiae strain
Ontology highlight
ABSTRACT:
ORGANISM(S): Streptococcus agalactiae
SUBMITTER: Violette DA CUNHA
PROVIDER: E-MEXP-3237 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Rga, a RofA-like regulator, is the major transcriptional activator of the PI-2a pilus in Streptococcus agalactiae.
Microbial drug resistance (Larchmont, N.Y.) 20120320 3
Rapid adaptation to changing environments is key in determining the outcome of infections caused by the opportunistic human pathogen Streptococcus agalactiae. We previously demonstrated that the RofA-like protein (RALP) regulators RogB and Rga activate their downstream divergently transcribed genes, that is, the pilus operon PI-2a and the serine-rich repeat encoding gene srr1, respectively. Characterization of the Rga regulon by microarray revealed that the PI-2a pilus was strongly controlled by ...[more]
