Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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An increase in the abundance of Tim23 in Arabidopsis thaliana results in the disruption of complex I and activation of mitochondrial biogenesis.


ABSTRACT: Analysis of changes in global transcript abundance profiles of 2 week old tim23 OE (overexpressor) and tim23 KO (knock-out) mutant Arabidopsis plants complared to wild-type (Col-0) using Affymetrix GeneChipル Arabidopsis ATH1 Genome Arrays.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Estelle Giraud 

PROVIDER: E-MEXP-3309 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Dual location of the mitochondrial preprotein transporters B14.7 and Tim23-2 in complex I and the TIM17:23 complex in Arabidopsis links mitochondrial activity and biogenesis.

Wang Yan Y   Carrie Chris C   Giraud Estelle E   Elhafez Dina D   Narsai Reena R   Duncan Owen O   Whelan James J   Murcha Monika W MW  

The Plant cell 20120622 6


Interactions between the respiratory chain and protein import complexes have been previously reported in Saccharomyces cerevisiae, but the biological significance of such interactions remains unknown. Characterization of two mitochondrial preprotein and amino acid transport proteins from Arabidopsis thaliana, NADH dehydrogenase B14.7 like (B14.7 [encoded by At2g42210]) and Translocase of the inner membrane subunit 23-2 (Tim23-2 [encoded by At1g72750]), revealed both proteins are present in respi  ...[more]

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