Shifting of immune responsiveness to house dust mite by influenza a infection genomic insights

ABSTRACT: House dust mite (HDM) extract (Greer Laboratories, Lenoir, NC) was resuspended in sterile phosphate-buffered saline (PBS) at a concentration of 0.5 mg (protein)/ml and 10 ul (5 ug dose) was administered to isofluorane-anesthetized mice intranasally. Groups of mice were infected either with influenza A or exposed to PBS. Seven days later, separate groups of mice were either exposed to saline or HDM for 3 or 6 days and lungs harvested 24 h after the last exposure, at day 4 (early phase; EP) or day 7 (late phase; LP).

ORGANISM(S): Mus musculus

SUBMITTER: Mainul Husain 

PROVIDER: E-MEXP-3325 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress