Transcription profiling of rat cerebral arteries from rats after experimental SAH with the expression in cerebral vessels from sham operated animals

ABSTRACT: We have compared the gene-expression in cerebral arteries from rats after experimental SAH with the expression in cerebral vessels from sham operated animals. The model is well characterised (Prunell et al. 2003; Prunell et al. 2004) regarding the physiological changes but not regarding the gene expression pattern. Male Sprague-Dawley rats (350-400 g) were anaesthetized using 5% halothane (Halocarbon Laboratories, River Edge, New Jersey) in N2O/O2 (30:70). The rat was intubated and artificially ventilated with inhalation of 0.5-1.5% halothane in N2O/O2 (70:30) during the surgical procedure. The depth of anaesthesia was carefully monitored and the respiration checked by regularly withdrawing arterial blood samples for blood gas analysis (Radiometer, Copenhagen, Denmark). An arterial cathet

ORGANISM(S): Rattus norvegicus

DISEASE(S): subarachnoid hemorrhage NOS

SUBMITTER: Petter Vikman 

PROVIDER: E-MEXP-338 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress