Dataset Information
BIGenomics_hpv_Agilent
Ontology highlight
ABSTRACT:
The aim of the experiment was to evaluate a HPV genotyping microarray method using patient sample DNA. HPV genotyping is based on multiplex PCR (PGMY-t primers) followed by ligation step where two probes are ligated together if a matching template is present in the mixture. The ligated probes are then detected on microarray.
ORGANISM(S): Human papillomavirus
SUBMITTER: Jarmo Ritari
PROVIDER: E-MEXP-3466 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Detection of human papillomaviruses by polymerase chain reaction and ligation reaction on universal microarray.
PloS one 20120323 3
Sensitive and specific detection of human papillomaviruses (HPV) in cervical samples is a useful tool for the early diagnosis of epithelial neoplasia and anogenital lesions. Recent studies support the feasibility of HPV DNA testing instead of cytology (Pap smear) as a primary test in population screening for cervical cancer. This is likely to be an option in the near future in many countries, and it would increase the efficiency of screening for cervical abnormalities. We present here a microarr ...[more]
