Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Loor-Mouse-mammary transcriptomics

ABSTRACT: Effect of supplemental trans-10,cis-12-CLA during lactation on mammary tissue gene expression profiles.

ORGANISM(S): Mus musculus

SUBMITTER: Juan Loor

PROVIDER: E-MEXP-3622 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue.

Kadegowda Anil K G AK Khan M Jawad MJ Piperova Liliana S LS Teter Beverly B BB Rodriguez-Zas Sandra L SL Erdman Richard A RA Loor Juan J JJ

Journal of lipids 20130514

Exogenous trans-10, cis-12-CLA (CLA) reduces lipid synthesis in murine adipose and mammary (MG) tissues. However, genomewide alterations in MG and liver (LIV) associated with dietary CLA during lactation remain unknown. We fed mice (n = 5/diet) control or control + trans-10, cis-12-CLA (37 mg/day) between d 6 and d 10 postpartum. The 35,302 annotated murine exonic evidence-based oligo (MEEBO) microarray and quantitative RT-PCR were used for transcript profiling. Milk fat concentration was 44% lo ...[more]

PMID: 23762566

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Dataset Information

Loor-Mouse-mammary transcriptomics

Publications

Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue.

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