Recurrence in non-muscle invasive bladder cancer

ABSTRACT: Although non muscle-invasive bladder cancer can be treated successfully by surgical resection, there is a high rate of recurrence, which frequently develops into an invasive form of cancer. Due to the lack of marker molecules to predict recurrence, it is currently recommended that after resection each patient is screened via cystoscopy at least twice a year. This results in a psychic burden to the patient and substantial economic costs to the health care system. Using antibody microarrays targeting 724 different cancer-related proteins, we studied protein profiles of patients with and without recurrence. The analysis revealed 255 proteins of differential abundance. Most are involved in the regulation and execution of apoptosis and cell proliferation. For prognosis, a signature of 20 protei

ORGANISM(S): Homo sapiens

SUBMITTER: Christoph Schroeder 

PROVIDER: E-MEXP-3625 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress