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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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MiR-126-126star in melanoma cell lines

ABSTRACT: Based on microRNA expression profiling studies, here we focus on miR-126&126* as the most downmodulated microRNAs in a panel of melanoma cell lines at different stages of progression compared with normal human melanocytes. At present no data exist on miR-126&126* possible role in melanoma. Our results show miR-126/miR-126* downregulation associated with tumor progression and the antineoplastic role deriving from their restored expression in metastatic melanomas in vitro as well as in vivo.

ORGANISM(S): Homo sapiens

SUBMITTER: nadia felli

PROVIDER: E-MEXP-3629 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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