Gene expression in the thymus medulla in the absence and presence of acute graft-versus-host disease

ABSTRACT: To investigate gene expression profile of medullary thymic epithelial cells with high surface density of MHC class II (mTEChigh), a murine parent into F1 hematopoietic stem cell transplantation model was administered. As recipient mice (B6xDBA/2)F1 (B6D2F1) were used that received either a syngeneic transplant from a (B6xDBA/2)F1 mouse or an allogeneic transplant from a B6 mouse, which leads to acute graft-versus-host disease (aGVHD). mTEChigh (CD45-EpCAM+Ly51-UEA1+MHCIIhigh) are sorted by FACS.

ORGANISM(S): Mus musculus

SUBMITTER: Simone Dertschnig 

PROVIDER: E-MEXP-3745 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress