MiR-99a let7c cluster

ABSTRACT: To investigate the function of miR99a/let-7c miRNAs during cardiomyogenesis, we decided to perturb their expression using transgenic mES cell lines the corresponding precursors (pre-miRNA) of the two miRNAs. We used the ROSA-TET system (EB3 tet off), in which the transgene is inserted in Rosa26 locus by Cre recombinase. We generated three different clones both miRNAs let-7c/miR-99a and those only one miRNA, namely the let-7cdeletedmiR-99a and the miR-99adeletedlet-7c.

ORGANISM(S): Mus musculus

SUBMITTER: Gilda Cobellis 

PROVIDER: E-MEXP-3748 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress