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Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptome wt vs mdxR mutant in E. faecium E1162 grown in BHI

ABSTRACT: Comparative transcriptome analysis of E. faecium E1162 and its isogenic mdxR deletion mutant during growth in BHI in mid-exponential phase (A660 = 0.3)

ORGANISM(S): Enterococcus faecium

SUBMITTER: Xinglin Zhang

PROVIDER: E-MEXP-3760 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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A LacI-family regulator activates maltodextrin metabolism of Enterococcus faecium.

Zhang Xinglin X Rogers Malbert M Bierschenk Damien D Bonten Marc J M MJ Willems Rob J L RJ van Schaik Willem W

PloS one 20130807 8

Enterococcus faecium is a gut commensal of humans and animals. In the intestinal tract, E. faecium will have access to a wide variety of carbohydrates, including maltodextrins and maltose, which are the sugars that result from the enzymatic digestion of starch by host-derived and microbial amylases. In this study, we identified the genetic determinants for maltodextrin utilization of E. faecium E1162. We generated a deletion mutant of the mdxABCD-pulA gene cluster that is homologous to maltodext ...[more]

PMID: 23951303

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