Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcriptome profiling of E. coli under different naphthoquinone treatments

ABSTRACT: E. coli MG1655 was grown in the presence of either PL (Plumbagin)/JU (Juglone)/ME (Menadione) (50 micro molar) and DMSO (0.75%)as control, and subjected to microarray analysis. The aim of the work was to understand the structure-function relationship between plumbagin and its analogues.

ORGANISM(S): Escherichia coli

SUBMITTER: Arun Sharma

PROVIDER: E-MEXP-3765 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Antimutagenic and antioxidant properties of plumbagin and other naphthoquinones.

Kumar Sanjeev S Gautam Satyendra S Sharma Arun A

Mutation research 20130517 1

The structure-function relationships of the naphthoquinone phytochemicals, plumbagin, juglone, and menadione, have been studied with regard to antimutagenic and antioxidant activities. Antimutagenicity of these compounds was assessed by the Ames test and RNA polymerase B (rpoB)-based rifampicin resistance assay. Antioxidant potential was evaluated by radical scavenging assays and reducing power measurement. Protection of cells and DNA against gamma radiation-induced oxidative damage was assayed ...[more]

PMID: 23688616

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Dataset Information

Transcriptome profiling of E. coli under different naphthoquinone treatments

Publications

Antimutagenic and antioxidant properties of plumbagin and other naphthoquinones.

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