Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression profiling of persistent polyclonal B cell lymphocytosis PPBL and control IgMpos B cell subsets


ABSTRACT: To study the nature of persistent polyclonal B cell lymphocytosis (PPBL), we purified CD27posIgMposIgDpos from 4 patients, as well as transitional (CD38hiCD24hi), pre-naive (CD38dimCD24dimCD5pos), naive mature (CD38dimCD24dimCD5-CD27-), natural effector (CD27posIgMposIgDpos) and IgM-only (CD27posIgMposIgDneg) B cells from healthy controls and performed genome-wide transcription profiling. We aimed to identify the control counterpart of PPBL cells and to study deregulated processes as compared to this control counterpart

ORGANISM(S): Homo sapiens

DISEASE(S): Persistent polyclonal B-cell lymphocytosis

SUBMITTER: Menno van Zelm 

PROVIDER: E-MEXP-3767 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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