Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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NsrR and ResD binding in Bacillus subtilis


ABSTRACT: The direct roles of the NO-sensitive NsrR repressor and the ResD response regulator in transcriptional control in Bacillus subtilis

ORGANISM(S): Bacillus subtilis

SUBMITTER: Shu Ishikawa 

PROVIDER: E-MEXP-3882 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The ResD response regulator, through functional interaction with NsrR and fur, plays three distinct roles in Bacillus subtilis transcriptional control.

Henares Bernadette B   Kommineni Sushma S   Chumsakul Onuma O   Ogasawara Naotake N   Ishikawa Shu S   Nakano Michiko M MM  

Journal of bacteriology 20131108 2


The ResD response regulator activates transcription of diverse genes in Bacillus subtilis in response to oxygen limitation. ResD regulon genes that are the most highly induced during nitrate respiration include the nitrite reductase operon (nasDEF) and the flavohemoglobin gene (hmp), whose products function in nitric oxide (NO) metabolism. Transcription of these genes is also under the negative control of the NO-sensitive NsrR repressor. Recent studies showed that the NsrR regulon contains genes  ...[more]

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