Transcriptional response of Pseudomonas aeruginosa PAO1 to human host defense peptide LL-37

ABSTRACT: In this experiment the transcriptional response of the opportunistic human pathogen Pseudomonas aeruginosa towards physiological concentrations of the major human host defense peptide LL-37 was investigated using microarrays. To this aim, three independent cultures of P. aeruginosa PAO1 were grown until mid-log phase in Mueller-Hinton broth and subsequently incubated with either sublethal LL-37 concencentrations (20 M-5g/ml) or without peptide for 2 h at 37 M-0C following RNA extraction and microarray analysis.

ORGANISM(S): Pseudomonas aeruginosa

SUBMITTER: Nikola Strempel 

PROVIDER: E-MEXP-3970 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress