Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

10 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Zn depletion - izh2 deletion vs. wild-type yeast

ABSTRACT: Comparison of gene expression in izh2delta cells and wild-type cells, under conditions of normal and limiting zinc concentration.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Uros Petrovic

PROVIDER: E-MEXP-3995 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Transcription profiling of rapamycin treated wild type and ume1-deletion yeast

Project description:Rapamycin treatment of wild type and ume1-delta yeast S. cerevisiae strain.

2008-09-04 | E-MEXP-1782 | biostudies-arrayexpress

Transcription profiling of SET-2 deletion and wild type yeast on sense and anti-sense arrays

Project description:The presence of Set2-mediated methylation of H3K36 (K36me) correlates with transcription frequency throughout the yeast genome. K36me targets the Rpd3S complex to deacetylate transcribed regions and suppress cryptic transcription initiation at certain genes. Here, using a genome-wide approach, we report that the Set2-Rpd3S pathway is generally required for controlling acetylation at coding regions. When using acetylation as a functional read-out for this pathway, we discovered that longer genes and, surprisingly, genes transcribed at lower frequency exhibit a stronger dependency. Moreover, a systematic screen using high resolution tiling microarrays allowed us to identify a group of genes that rely on Set2-Rpd3S to suppress spurious transcripts. Interestingly, most of these genes are within the group that depend the same pathway to maintain a hypo-acetylated state at coding regions. These data highlight the importance of using the functional readout of histone codes to define the roles of specific pathways.

2009-03-03 | E-TABM-265 | biostudies-arrayexpress

Isw1 and Chd1 maintain chromatin organization during transcription [isw1 chd1 mutant expression]

Project description:Gene expression microarray experiments to determine the existence of intragenic (cryptic) transcripts in an isw1 chd1 mutant yeast strain. Two color experiment. Mutant/WT. Biological replicates=3. Hybridisation of same samples to strand-specific gene expression arrays.

2012-07-24 | E-GEOD-37158 | biostudies-arrayexpress

Antisense Cryptic transcription in histone H3 K36A, K56R and K36AK56R mutant yeast strain compared to wild-type

Project description:Gene expression microarray experiments to determine the existence of intragenic (cryptic) transcripts in K36A, K56R and K36AK56R mutant yeast strain compared to wildtype. Two color experiment. Mutant/WT. Biological replicates=3. Hybridisation of same samples to strand-specific gene expression arrays.

2012-07-24 | E-GEOD-37042 | biostudies-arrayexpress

Sense Cryptic transcription in histone H3 K36A, K56R and K36AK56R mutant yeast strain compared to wild-type

2012-07-24 | E-GEOD-37102 | biostudies-arrayexpress

rogB mutant in NEM316 S. agalactiae strain

Project description:transcritpomic analysis of rogB mutant in NEM316 S. agalactiae strain

2012-05-21 | E-MEXP-3237 | biostudies-arrayexpress

Transcription profiling by array of abx1 deletion or over expression in Streptococcus agalactiae and comparision with the effect of CovS and CovR deletion

Project description:Analysis of the impact of the abx1 deletion or over expression on S. agalactaie transcription profile and comparision to the effect of CovS and CovR deletion on transcriptomic profile. Some of the mutants are gene_knock_out mutants, but in other strains we have tested the over expression of the Abx1 protein by an chromosomic overexpression, or by a plasmid overexpression. Chromosomic overexpression is indicated with a K and plasmid overexpression with a V.

2013-02-26 | E-MEXP-3703 | biostudies-arrayexpress

rga response

Project description:comparison of the transcriptionnal response of the rga mutant and the wild type in S. agalactiae NEM316 strain

2012-05-21 | E-MEXP-3236 | biostudies-arrayexpress

Analysis of Streptococcus agalactiae response to dltA mutation the role of DltR

Project description:Analysis of S. agalactiae response to dltA mutation the role of DltR. This analysis is based on the comparison of the effect of dltA and dltR mutation on S. agalactiae transcription profile.

2014-05-25 | E-MEXP-3317 | biostudies-arrayexpress

CovRS response in S. agalactiae NEM316 strain

Project description:Analysis of the CovRS response in S. agalactiae NEM316 strain with microarrays

2012-05-21 | E-MEXP-3304 | biostudies-arrayexpress