Dataset Information
Transcription profiling of zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection
Ontology highlight
ABSTRACT:
ORGANISM(S): Danio rerio
DISEASE(S): fish tuberculosis
SUBMITTER: herman spaink
PROVIDER: E-MEXP-405 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection.
Molecular immunology 20050112 10
The Mycobacterium marinum-zebrafish infection model was used in this study for analysis of a host transcriptome response to mycobacterium infection at the organismal level. RNA isolated from adult zebrafish that showed typical signs of fish tuberculosis due to a chronic progressive infection with M. marinum was compared with RNA from healthy fish in microarray analyses. Spotted oligonucleotide sets (designed by Sigma-Compugen and MWG) and Affymetrix GeneChips were used, in total comprising 45,46 ...[more]
