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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human embryonic kidney cells expressing apoptosis inducing proteins, time series

ABSTRACT: Three apoptosis inducing proteins, ACO1, STK3 and XBP1 were discovered in a previous reverse transfection screen. HEK293T cells were harvested and RNA extracted from the cells after over-expression of these 3 proteins at 12, 24 and 48 hours. A positive apoptosis inducer staurosporine and a negative control transfection reagent only were also included at each time point. Each sample had an experimental replicate.

ORGANISM(S): Homo sapiens

SUBMITTER: Ella Palmer

PROVIDER: E-MEXP-421 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays.

Yap Yee Leng YL Lam David C L DC Luc Girard G Zhang Xue Wu XW Hernandez David D Gras Robin R Wang Elaine E Chiu S W SW Chung Lap Ping LP Lam W K WK Smith David K DK Minna John D JD Danchin Antoine A Wong Maria P MP

Nucleic acids research 20050114 1

Gene transcription in a set of 49 human primary lung adenocarcinomas and 9 normal lung tissue samples was examined using Affymetrix GeneChip technology. A total of 3442 genes, called the set M AD, were found to be either up- or down-regulated by at least 2-fold between the two phenotypes. Genes assigned to a particular gene ontology term were found, in many cases, to be significantly unevenly distributed between the genes in and outside M AD. Terms that were overrepresented in M AD included func ...[more]

PMID: 15653641

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