Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of known iron genes in liver, spleen and duodenum of C57BL/6J and SWR mouse strains which have low and high basal iron levels respectively

ABSTRACT: Comparison of expression of known 'iron' genes in liver, spleen and duodenum of C57BL/6J and SWR mouse strains which have low and high basal iron levels respectively.

INSTRUMENT(S): GenePix Professional 4200A [Axon Instruments]

ORGANISM(S): Mus musculus

SUBMITTER: Gemma Grant 

PROVIDER: E-MEXP-486 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Multiple polymorphic loci determine basal hepatic and splenic iron status in mice.

Grant Gemma R GR   Robinson Susan W SW   Edwards Richard E RE   Clothier Bruce B   Davies Reginald R   Judah David J DJ   Broman Karl W KW   Smith Andrew G AG  

Hepatology (Baltimore, Md.) 20060701 1

Polymorphisms of genes linked to iron metabolism may account for individual variability in hemochromatosis and iron status connected with liver and cardiovascular diseases, cancers, toxicity, and infection. Mouse strains exhibit marked differences in levels of non-heme iron, with C57BL/6J and SWR showing low and high levels, respectively. The genetic basis for this variability was examined using quantitative trait loci (QTL) analysis together with expression profiling and chromosomal positions o  ...[more]

Similar Datasets

Transcriptomics Transcription profiling of 4 week old BALB/c_Fech m1Pas mice (Fech) vs with 4 week old control BALB/c mice
2005-10-21 | E-MEXP-194 | biostudies-arrayexpress
Transcriptomics Effects of upf1delta on RNA stability
2013-06-03 | E-MTAB-1324 | biostudies-arrayexpress
Transcriptomics Effects of upf2delta and upf3delta on gene expression
2013-06-03 | E-MTAB-1325 | biostudies-arrayexpress
Transcriptomics Effects of deletion of genes encoding RNA-binding proteins on gene expression in S. pombe
2014-11-06 | E-MTAB-2314 | biostudies-arrayexpress
Transcriptomics MicroRNA profiling of human breast cancer cell line MCF7 under conditions of hypoxia
2008-03-01 | E-MEXP-1111 | biostudies-arrayexpress
Transcriptomics Effects of deletion of RNA-binding proteins on RNA stability
2014-11-06 | E-MTAB-2712 | biostudies-arrayexpress
Transcriptomics Transcription profiling of hyperthermophilic crenarchaea Sulfolobus solfataricus and Sulfolobus acidocaldarius to UV irradiation
2007-11-21 | E-MEXP-1252 | biostudies-arrayexpress
Transcriptomics Role of the Ccr4/Not complex in the regulation of heterochromatin in Schizosaccharomyces pombe (IV)
2015-09-25 | E-MTAB-3059 | biostudies-arrayexpress
Transcriptomics Role of the Ccr4/Not complex in the regulation of heterochromatin in Schizosaccharomyces pombe (V)
2015-09-25 | E-MTAB-3060 | biostudies-arrayexpress
Transcriptomics Role of the Ccr4/Not complex in the regulation of heterochromatin in Schizosaccharomyces pombe (VII)
2015-09-25 | E-MTAB-3493 | biostudies-arrayexpress