Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of basal transcription levels in normal and radiation sensitive primary human fibroblasts

ABSTRACT: 1. effect of radiation on transcription in normal and radiation sensitive primary human fibroblasts. 2. comparison of the basal transcription levels in normal and radiation sensitive primary human fibroblasts.

INSTRUMENT(S): G2565BA DNA microarray scanner [Agilent]

ORGANISM(S): Homo sapiens

SUBMITTER: Eniko Kis

PROVIDER: E-MEXP-512 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray analysis of radiation response genes in primary human fibroblasts.

Kis Enikö E Szatmári Tünde T Keszei Márton M Farkas Róbert R Esik Olga O Lumniczky Katalin K Falus András A Sáfrány Géza G

International journal of radiation oncology, biology, physics 20061025 5

<h4>Purpose</h4>To identify radiation-induced early transcriptional responses in primary human fibroblasts and understand cellular pathways leading to damage correction.<h4>Methods and materials</h4>Primary human fibroblast cell lines were irradiated with 2 Gy gamma-radiation and RNA isolated 2 h later. Radiation-induced transcriptional alterations were investigated with microarrays covering the entire human genome. Time- and dose dependent radiation responses were studied by quantitative real-t ...[more]

PMID: 17069989

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Dataset Information

Transcription profiling of basal transcription levels in normal and radiation sensitive primary human fibroblasts

Publications

Microarray analysis of radiation response genes in primary human fibroblasts.

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